The new tax laws will limit the amount of interest payments you can deduct up to $750,000 if you've financed your B&B with a mortgage. If you have a business loan, this limit does not apply.
Anyone who itemizes can deduct their property taxes, but filers must choose between deducting their state & local property, income taxes, or deducting their sales taxes. Again, I believe this only applies to B&Bs owned as homes, not businesses.